PhytoRetinol™ has been confirmed to tighten collagen fibers. The expression of Fibrin4, which is the source of elastin protein is increased, and integrin α1, which binds the basement membrane, the dermis and laminin 5, which is the adhesive of the basement membrane are also all increased. Hyaluronidase activity, in turn, is inhibited .
The resultant product produces a plant-derived retinol-like action and proven to safely improve fine wrinkles due to drying.