Name: Scale up or Scale out: Decode the Platform Selection Dilemma
Start: 2025-04-03T06:00:00Z
End: 2025-04-03T06:01:00.000Z
Location: BrightTALK
Rating: 0

The Corning Scientific Seminar Series is a series of free, online technical presentations that provide novel tips, best practices and proven techniques to help advance your research. Delivered by scientists to scientists, these one-hour broadcasts offer useful information and tips for lab technicians and researchers.

本ウェビナーでは、他家細胞治療薬の量産化を目指す皆さまに向けて、「CellCubeシステム」をご紹介します。さらに、株式会社S-Quatreが開発を進めるヒト脱落乳歯由来幹細胞（SHED）を用いた成功事例についても解説を行います。商用化を見据えた製造プロセス設計や、コスト最適化のポイントをお届けします。

Corning® CellCube® システムを活用した他家間葉系幹細胞（MSC）治療薬の高効率製造プロセス

Join us for an insightful webinar on enhancing lab sustainability with Corning. Discover innovative strategies to create an eco-friendlier lab environment and how Corning can support your green initiatives. This session will explore three key areas of action: reducing energy consumption, minimizing waste, and optimizing lab processes for maximum efficiency and sustainability.

How to Boost Lab Sustainability with Corning

Gayatri (Gaya) Kasi has 8 years of product experience ranging from product engineering, product management, and now, product sustainability. Kasi has a bachelor's degree in Chemical Engineering from Worcester Polytechnic Institute and is currently on a path to get her MBA from Boston University with a concentration in Health Sector Management. In her current role as a Product Sustainability Portfolio Manager for Corning Life Sciences, she utilizes her engineering and business background to view sustainability from a design perspective to overcome challenges with single use plastics. Her mission is to innovate and drive adoption of sustainable products and circular solutions while maintaining product performance and quality as the most critical attributes for lifesaving research and production.

Join us on April 29, 2025, at 11:00 a.m. EST to learn the ten ways to boost lab sustainability, covering information on creating a smarter lab, and how Corning can help you go green. Moving toward a greener lab involves thinking about three main categories for action: reducing energy use, choosing consumables that minimize waste, and optimizing lab processes to support sustainability.

10 Ways to Boost Lab Sustainability

This talk will highlight the importance of vendor selection, media storage, media usage, and contamination control strategies in efforts to guide scientists to find the right media formulations for their processes. With so many media vendors and options for media out there, how do you choose what is right for your current process and for your long-term process goals? Learn about key factors that can impact your decision when choosing a media vendor.

Cell Culture Media Quality Control Strategies

During this presentation, we will focus on how enhanced cryopreservation can significantly boost post-thaw revival, viability, and effectiveness. We will delve into the fundamental processes of cryopreservation and provide recommendations for handling. 

Tom Bongiorno is a Senior Support Scientist at Corning Life Sciences. He has expertise in stem cell therapy, bioprocessing, media development, and cryopreservation. Tom holds a Ph.D. in bioengineering from the Georgia Institute of Technology and a bachelor's degree in mechanical engineering from the University of Notre Dame.

Best Practices for Mammalian Cell Cryopreservation

Since 2017 more than 35 cell and gene therapy products have gained FDA approval. Despite the rapid growth of the cell and gene therapy (CGT) sector, many challenges remain, including high costs, complex manufacturing processes, and contamination risks. Implementing standard and customized closed-system solutions can significantly improve efficiency, safety, and cost-effectiveness in CGT manufacturing.  

In this webinar, we will address how closed system solutions offer process flexibility, reduce contamination risks, and can contribute to time saving or simplifying steps in manufacturing.  

This webinar will introduce viewers to Corning’s closed system solutions, with attention to the following topics:  
- Assembly and customization of closed systems.  
- Closed system process considerations and flexibility in design 
- Scaling up and out using closed systems.  
- Customization to build own closed system solution. 

Attend this webinar to learn more about: Benefits of closed systems, Customized solutions, Key considerations for closed system design.

Closed System and Custom Solutions for Bioproduction

Cell attachment is a critical yet often overlooked factor in successful cell culture. Poor adhesion can lead to reduced cell viability, inconsistent results, and compromised experimental outcomes. In this webinar, we will demystify the science of cell attachment, covering the key mechanisms, common challenges that hinder adhesion, and practical strategies to improve cell attachment efficiency. We will explore why cells fail to attach, troubleshooting strategies, and best practices for optimizing cell culture conditions. We will also introduce Corning’s advanced cell culture surfaces including Corning® BioCoat™, PureCoat™, Synthemax® II, and CellBIND® surfaces etc, designed to enhance cell adhesion in standard and serum-free conditions. Through case studies, we will demonstrate how researchers have successfully improved cell attachment using these specialized culture surfaces.

De-mystifying cell attachment – science, challenges, and practical solutions

Good cell conditions are vital to successful research. In this presentation, we will introduce some common situations that cause cell growth problems and the solution to prevent the problems. You will learn: 
- How to monitor cell conditions and keep cells “happy”.  
- Types of common contamination and the solutions. 
- Why good procedure technique can prevent cell growth problems.

Cell Culture Fundamentals: Identify and Correct Common Cell Growth Problems

This webinar will cover:
- Choosing the right surface and media
- Good practices for pipetting
- Cryopreservation of samples

Cell Culture Fundamentals: Cryopreservation, Pipetting, and More

Minimizing the risk of cell culture contamination is crucial to avoid wasting time, money, and effort. Discover effective ways to reduce contamination and optimize your work for improved results.

From this informative webinar, you will gain insight into:
• Identifying common cell culture contaminants
• Distinguishing between biological and chemical contaminants
• Understanding the sources of contamination
• How to effectively control cell culture contamination

Understanding and Managing Cell Culture Contamination

In the evolving field of cell culture and cell therapy, scaling up production while maintaining cell quality is critical. Corning’s CellCube system offers a robust, scalable solution designed to support high-density cell culture with efficient use of space and resources. 
In this webinar we will: 
- Discuss CellCube technology and capabilities.
- Introduce the setup of CellCube with bioreactor or disposable spinner flask.
- Share tips and tricks for workflow optimization.
- Show you can achieve yields of 1 billion Bone Marrow-derived Mesenchymal Stem Cell with one CellCube 25 vessel.
Whether you're working in research, bioproduction, or cell therapy development, join us to learn how CellCube can enhance your cell culture processes and help achieve consistent, high-quality scaling up production.

Enhancing Attachment-dependent Cell Yields with Corning® CellCube® system: Advanced Strategies for Scalable Cell Culture

本ウェビナーでは、ヒト間葉系幹細胞のスケールアップ工程を構築する上で考慮すべき要素や50L バイオリアクター培養系開発過程の解説、Corning® 低濃度 Synthemax® II マイクロキャリアを用いた50L バイオリアクター培養系の改善例についてご紹介します。

ヒト間葉系幹細胞（MSC）におけるマイクロキャリアを利用した50L バイオリアクター培養

3D cell culture is gaining traction as an attractive alternative to traditional cell culture methods. As the field is advancing with remarkable creativity and enthusiasm, we continue to unearth new findings that differ from our experience with 2D cell culture research or even unshackle us from the limit of 2D cell culture. This proves critical in research areas such as developmental biology, cancer biology, drug discovery and especially personalized medicine. Corning cell culture product portfolio proudly covers a vast range of 3D cell culture need. Join us in this webinar to explore paradigm-shifting applications and if 2D cell culture are holding you back and familiarize yourself with the most common 3D cell culture workflows.

Treating the 3D trouble

Are you looking to enhance the performance of your cell culture systems?
We will explore Corning’s advanced surface technologies, designed to optimized cell culture performance for a wide range of applications.
This webinar will delve into Corning’s innovative surface modifications such as Ultra-Low Attachment(ULA), CellBIND and Advanced TC surfaces.
These surfaces offer enhanced cell culture capabilities allowing you to overcome challenges associated with complex cell types and advanced assays.
Whether you’re working in stem cell research, regenerative medicine or 3D cell culture, Corning’s advanced surface technologies can help elevate your experimental outcomes.
Corning’s advanced surfaces can revolutionize your research and bring your cell culture experiments to the next level.

Find the “RIGHT” culture surface - Enhancing Cell Culture Performance for Better Results

This webinar will focus on the technical side of PYREX products, such as why glass breaks and how to prevent it, general cleaning recommendations,  and when to use plastic instead. You will also learn about our PYREXPLUS and Low Actinic line extensions.

PYREX® Glassware Education and Safety

In this webinar the following topics will be covered:
- The difference between 2D and 3D cell culture and the benefits of moving to 3D cell culture
- Different 3D cell culture systems and their applications
- Corning solutions available to streamline and improve 3D workflows

Making the Transition from 2D to 3D

Significant advancements in upstream biomanufacturing methods for cell and gene therapies have been achieved in recent years. However, final yields continue to be impacted by losses in downstream steps. Interferometric Light Microscopy (ILM) represents a fast and cost-effective method for process development teams to obtain size and concentration data within seconds. This presentation will cover the technical basis of ILM as it compares to other methods for monitoring nanoparticles. Experimental studies developing ILM utilization in characterizing virus preparations, detecting virus breakage and aggregation, and monitoring lipid nanoparticle preparations will be discussed.

Interferometric Light Microscopy for Rapid Virus Titering and Characterization of Lipid Nanoparticle Preparations

Breakthrough medical innovations are transforming the way we treat and potentially cure certain diseases. There are challenges like scalability, automation, cell type flexibility, that must be solved. A critical parameter for that can affect time to market and production costs is platform selection. Also, when addressing the question of commercial viability, therapeutics developers face these crucial questions.
Join us for reviewing the platforms and processes that can go from research to production while minimizing technology transfer or re-development, that support multiple cell types and workflows including vaccines, cell and gene therapy, regenerative medicine.

Scale up or Scale out: Decode the Platform Selection Dilemma

platform selection

cell culture

cell and gene therapy

vaccine

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Scale up or Scale out: Decode the Platform Selection Dilemma

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