Name: Strategies for Scaling Up and Out in Gene Therapy Manufacturing
Start: 2023-06-12T14:48:00Z
End: 2023-06-12T14:48:47.000Z
Location: BrightTALK
Rating: 0

The Corning Scientific Seminar Series is a series of free, online technical presentations that provide novel tips, best practices and proven techniques to help advance your research. Delivered by scientists to scientists, these one-hour broadcasts offer useful information and tips for lab technicians and researchers.

Minimizing the risk of cell culture contamination is crucial to avoid wasting time, money, and effort. Discover effective ways to reduce contamination and optimize your work for improved results.

From this informative webinar, you will gain insight into:
• Identifying common cell culture contaminants
• Distinguishing between biological and chemical contaminants
• Understanding the sources of contamination
• How to effectively control cell culture contamination

Understanding and Managing Cell Culture Contamination

In the evolving field of cell culture and cell therapy, scaling up production while maintaining cell quality is critical. Corning’s CellCube system offers a robust, scalable solution designed to support high-density cell culture with efficient use of space and resources. 
In this webinar we will: 
- Discuss CellCube technology and capabilities.
- Introduce the setup of CellCube with bioreactor or disposable spinner flask.
- Share tips and tricks for workflow optimization.
- Show you can achieve yields of 1 billion Bone Marrow-derived Mesenchymal Stem Cell with one CellCube 25 vessel.
Whether you're working in research, bioproduction, or cell therapy development, join us to learn how CellCube can enhance your cell culture processes and help achieve consistent, high-quality scaling up production.

Enhancing Attachment-dependent Cell Yields with Corning® CellCube® system: Advanced Strategies for Scalable Cell Culture

本ウェビナーでは、ヒト間葉系幹細胞のスケールアップ工程を構築する上で考慮すべき要素や50L バイオリアクター培養系開発過程の解説、Corning® 低濃度 Synthemax® II マイクロキャリアを用いた50L バイオリアクター培養系の改善例についてご紹介します。

ヒト間葉系幹細胞（MSC）におけるマイクロキャリアを利用した50L バイオリアクター培養

3D cell culture is gaining traction as an attractive alternative to traditional cell culture methods. As the field is advancing with remarkable creativity and enthusiasm, we continue to unearth new findings that differ from our experience with 2D cell culture research or even unshackle us from the limit of 2D cell culture. This proves critical in research areas such as developmental biology, cancer biology, drug discovery and especially personalized medicine. Corning cell culture product portfolio proudly covers a vast range of 3D cell culture need. Join us in this webinar to explore paradigm-shifting applications and if 2D cell culture are holding you back and familiarize yourself with the most common 3D cell culture workflows.

Treating the 3D trouble

Are you looking to enhance the performance of your cell culture systems?
We will explore Corning’s advanced surface technologies, designed to optimized cell culture performance for a wide range of applications.
This webinar will delve into Corning’s innovative surface modifications such as Ultra-Low Attachment(ULA), CellBIND and Advanced TC surfaces.
These surfaces offer enhanced cell culture capabilities allowing you to overcome challenges associated with complex cell types and advanced assays.
Whether you’re working in stem cell research, regenerative medicine or 3D cell culture, Corning’s advanced surface technologies can help elevate your experimental outcomes.
Corning’s advanced surfaces can revolutionize your research and bring your cell culture experiments to the next level.

Find the “RIGHT” culture surface - Enhancing Cell Culture Performance for Better Results

This webinar will focus on the technical side of PYREX products, such as why glass breaks and how to prevent it, general cleaning recommendations,  and when to use plastic instead. You will also learn about our PYREXPLUS and Low Actinic line extensions.

PYREX® Glassware Education and Safety

In this webinar the following topics will be covered:
- The difference between 2D and 3D cell culture and the benefits of moving to 3D cell culture
- Different 3D cell culture systems and their applications
- Corning solutions available to streamline and improve 3D workflows

Making the Transition from 2D to 3D

Significant advancements in upstream biomanufacturing methods for cell and gene therapies have been achieved in recent years. However, final yields continue to be impacted by losses in downstream steps. Interferometric Light Microscopy (ILM) represents a fast and cost-effective method for process development teams to obtain size and concentration data within seconds. This presentation will cover the technical basis of ILM as it compares to other methods for monitoring nanoparticles. Experimental studies developing ILM utilization in characterizing virus preparations, detecting virus breakage and aggregation, and monitoring lipid nanoparticle preparations will be discussed.

Interferometric Light Microscopy for Rapid Virus Titering and Characterization of Lipid Nanoparticle Preparations

Cancer research continues to be a vast domain of scientific endeavors. This expansive field involves the exploration of cancer biology, tumor development, cellular processes, and treatment modalities. The complexity of cancer’s interaction with the immune system, its resistance to therapy, and its diverse manifestation across different tissues necessitate continuous effort, in both basic and translation research. Advances in technology and capability, of which Corning is proud to be a part of, continue to enhance our understanding of cancer, driving progress toward more effective and individualized treatments. This talk provides an overview of how Corning products can contribute to your cancer workflow.

Conquering Cancer: how Corning creates capability

Join us on September 5 for an introduction to assay development. Hosted by Hilary Sherman, this webinar will cover: 
-Types of assays
-Modes of detection
-Choosing the right microplate

Introduction to Assay Development

Microcarrier technology has revolutionized large-scale cell culture by providing a more efficient and scalable method for growing adherent cells. In this webinar, we will explore advanced strategies and practical tips for optimizing microcarrier cell culture. Attendees will gain insights into selecting the right microcarriers, fine-tuning culture conditions, and scaling up production while maintaining cell viability and productivity. We will also talk about how Corning dissolvable microcarriers could bring about better attachment and much easier cell harvest and streamline your bioprocess. Whether you're a seasoned researcher or new to microcarrier systems, this session will provide valuable knowledge to enhance your cell culture processes.

Bioprocess Intensification: Harnessing the Power of Microcarriers

PCR, Polymerase Chain Reaction, is the cornerstone of current molecular biology. Across diverse fields such as drug discovery, developmental biology, and bioinformatics, PCR is a critical method for elucidating gene expression of interest. Whether performed in tubes, strips, or plates, this fundamental technique simply reveals if a gene is activated and to what extent, either qualitatively or quantitatively. Alongside an introduction to PCR and the troubleshooting, we are here to introduce Corning’s end-to-end solutions for PCR and genomics workflows, emphasizing our commitment to quality assurance as evidenced by our Certificates of Analysis and Certificates of Compliance—often overlooked but providing the utmost assurance and peace of mind for our users.

Many a Little Makes a Mickle - PCR: Genomics Workflow

本ウェビナーでは、2D細胞培養と3D細胞培養の培養法の違いや利用できるアプリケーションを解説します。また、3D細胞培養のワークフローの効率化や改善に向けた提案についてもご紹介します。

2D培養と3D培養：3D細胞培養への移行の利点

Join us on July 18, 2024, for a live webinar presented by Jesus Martinez, Laboratory Glass Product Line Manager at Corning Life Sciences. During this presentation we will discuss:
- The PYREX brand history
- Product line innovation
- Unique advantages that have made PYREX labware a household name
- Commitment to the quality you deserve

PYREX® Labware: 100+ Years of History

Culture medium and serum are the first thing we consider from the beginning of cell culture. As the home of cells, it supports the growth and productivity of cells, from bench to production. Join us as we will explore the criticality of culture medium and serum. We will discuss on how we can increase productivities. With Corning's solution, we can overcome the cultivation bottlenecks with tailored medium and additives.

Media and Sera, Sweet Home of Cells

This webinar will cover: 
•Choosing the right surface and media
•Good practices for pipetting
•Cryopreservation of samples

Cell Culture Fundamentals: Cryopreservation, Pipetting, and More

細胞培養の研究では、それぞれの実験でどのような培養表面を選択するかは悩ましいものです。この課題に直面した時、様々な培養表面の特長や情報の入手方法を知ることでより良い選択が出来るようになります。今回は、コーニングがその長い歴史の中で開発し続けてきた細胞培養用表面について、研究者の皆様からいただく相談内容も含めてご紹介いたします。

コーニングの細胞培養表面とその活用例

Many mammalian cells, including stem cells and cancer cells, rely on scaffolding for 3D cell cultures. Selecting appropriate hydrogels to create a physiologically relevant microenvironment in these cultures has long been a grand challenge.

Presented by Dr. Xiuzhi Susan Sun, University Distinguished Professor at Kansas State University, and Elizabeth Abraham, New Product Strategy Director at Corning Life Sciences, this webinar will cover:
- Hydrogel selections and their impact on unlocking the potential of pluripotent stem cells (PSCs)
- The complexities of maintaining and expanding human induced pluripotent stem cells (hiPSCs)
- Advanced techniques for generating in vitro tumor models that faithfully mimic the physiological conditions of in vivo mouse models

Advanced Synthetic Peptide Hydrogel for Physiologically Relevant 3D Cell Culture

Designing a Recipe for Stem Cell Therapy Success

Closed System Solutions for Cell and Gene Therapy Manufacturing

Accelerating cancer therapies development: platform, process, and partnership

Tailor Your Cell Culture Platform to Achieve Objectives & Scale Requirements

Gene Therapy 2.0: Leveraging Transgene Cassette Engineering

Corning® Ascent® FBR - Innovative technology for scalable adherent cell culture

Bringing Gene Therapies to Life: Navigating Scale Up, Partnerships, and Barriers

Bioprocess Webinars

In this Expert Roundtable discussion, three experts speak about the challenges the rapidly expanding gene therapy field is facing in scaling up adeno-associated vector manufacturing, and the potential solutions.

Strategies for Scaling Up and Out in Gene Therapy Manufacturing

Life Sciences

gene therapy

aav manufacturing

adeno-associated vector

gene therapy manufacturing

scaling gene therapy

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Strategies for Scaling Up and Out in Gene Therapy Manufacturing

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