This is the 1st event of the 2023 ETSI ZSM Webinar Series. This webinar will describe how the ZSM framework can be used for the cross-domain management and orchestration of end-to-end services. Based on the ETSI specification ZSM 008, it will cover the lifecycle management processes for the onboarding, fulfilment and assurance of general end-to-end services and will demonstrate how these processes can be realized leveraging the northbound interfaces of different technology domains, such as 3GPP Radio Access, Fixed Access, 3GPP Core and Transport, to realize these processes across different technology domains. Further, the mechanisms defined by ETSI ZSM 003 for the management and orchestration of network slices will be introduced. Finally, two proofs of concept (PoCs) demonstrating the ZSM end-to-end approach will be presented. The PoCs focus on autonomy, as well as on service scaling in multisite environments.